Women taking Fosamax for several years may be prone to femur fractures

Bisphosphonates (Fosamax, Boniva, Actonel, Reclast), along with calcium and vitamin D supplementation, are a common conventional treatment for osteoporosis. These drugs are even used for prevention of osteoporosis in those with osteopenia.x-ray
Bone tissue continually goes through a cycle of formation of new bone and breakdown of old bone. Bisphosphonates increase bone mineral density in the short term by reducing bone breakdown, essentially reducing bone loss. However, it is not the same as building natural, healthy bone with exercise.  Exercise is essential, and, in particular, exercising the back and legs. Muscle strength is the most accurate way of predicting bone strength and of predicting risk of falls. Strengthening muscles has been shown to be the most effective way to strengthen bone and protect against osteoporosis-related fractures.1 Compared to exercise, medications are relatively ineffective and may cause harm.

Since bisphosphonates accumulate in bone tissue and suppress bone turnover, there has been a concern about the strength and integrity of the medically treated bone. Apparently, the use of bisphosphonates actually causes the bones to become brittle despite the increase seen in bone mineral density. 

Several studies have reported the occurrence of specific and rare types of femur fractures in individuals (mostly women) who had been taking bisphosphonates, specifically alendronate (Fosamax), for approximately 4-8 years.2,3,4,5,6,7,8,9Two additional and more recent studies  have drawn more attention to this potential hazard.10 Long term users of alendronate (Fosamax) – were found to be at significantly higher incidence of fractures.11 A frightening detail of these reports is that the fractures had occurred under minimal trauma – these fractures are not from falls. In fact, in most cases, these women were performing low-energy exercise, sometimes just walking down a flight of stairs.12,13

These medications have other serious side effects as well, such as atrial fibrillation a heart rhythm disturbance. Prevention of osteoporosis and bone fractures does not need to involve potentially dangerous drugs. 

Primary causes of hip fractures

  • Poor nutrition
  • Sedentary lifestyle
  • Muscle weakness
  • Side effects of prescription drugs
  • Declining vision
  • Cigarette smoking
  • Vitamin D deficiency

Exercise is a crucial component of my recommendations - most hip fractures result from falls. So, naturally, by increasing muscle strength and balance you can improve stability and prevent these falls.14 

My recommendations for osteoporosis protection: 

1.      Eat a high nutrient diet

2.      Take the right supplements.

3.      Do the right osteoporosis fighting exercises. Swimming and biking will not do it. The best bone building exercises designed to strengthen muscles and bone and to improve balance, reducing the risk of falls are demonstrated in my DVD  Osteoporosis Protection For Life

Osteoporosis Protection for Life                                

Dr. Fuhrman's Osteoporosis Protection For Life DVD is an educational and invigorating program for combating osteopenia and osteoporosis that offers a significant improvement over drug-treatment. In this video, Dr. Fuhrman offers advice regarding diet, supplements, and exercise, and demonstrates the best exercises to effectively build strength and bone mass.


1 Rubin C, Turner AS, Muller R, et al. Quantity and quality of trabecular bone in the femur are enhanced by a strongly anabolic, noninvasive mechanical intervention. J Bone Min Res 2002;17:349-357.

2 Cermak K, Shumelinsky F, Alexiou J, et al. Case Reports: Subtrochanteric Femoral Stress Fractures after Prolonged Alendronate Therapy. Clin Orthop Relat Res. 2009 Dec 18. [Epub ahead of print]

3 Capeci CM, Tejwani NC. Bilateral low-energy simultaneous or sequential femoral fractures in patients on long-term alendronate therapy. J Bone Joint Surg Am. 2009 Nov;91(11):2556-61.

4 Goddard MS, Reid KR, Johnston JC, Khanuja HS. Atraumatic bilateral femur fracture in long-term bisphosphonate use. Orthopedics. 2009 Aug;32(8). pii: orthosupersite.com/view.asp?rID=41933..

5 Ing-Lorenzini K, Desmeules J, Plachta O, et al. Low-energy femoral fractures associated with the long-term use of bisphosphonates: a case series from a Swiss university hospital. Drug Saf. 2009;32(9):775-85.

6 Lenart BA, Lorich DG, Lane JM. Atypical fractures of the femoral diaphysis in postmenopausal women taking alendronate. N Engl J Med. 2008 Mar 20;358(12):1304-6.

7 Sayed-Noor AS, Sjödén GO. Case reports: two femoral insufficiency fractures after long-term alendronate

therapy. Clin Orthop Relat Res. 2009 Jul;467(7):1921-6. Epub 2009 Feb 6.

8 Neviaser AS, Lane JM, Lenart BA, et al. Low-energy femoral shaft fractures associated with alendronate use. J Orthop Trauma. 2008 May-Jun;22(5):346-50.

9 Kwek EB, Goh SK, Koh JS, Png MA, Howe TS. An emerging pattern of subtrochanteric stress fractures: a long-term complication of alendronate therapy? Injury. 2008 Feb;39(2):224-31. Epub 2008 Jan 28.

10 LA Times: http://latimesblogs.latimes.com/booster_shots/2010/03/bisphosphonates-osteoporosis-medications.html


11 Somford MP, Draijer FW, Thomassen BJ, et al. Bilateral fractures of the femur diaphysis in a patient with rheumatoid arthritis on long-term treatment with alendronate: clues to the mechanism of increased bone fragility. J Bone Miner Res. 2009 Oct;24(10):1736-40.

12 Somford MP, Geurts GF, den Teuling JW, et al. Long-Term Alendronate Use Not without Consequences? Int J Rheumatol. 2009;2009:253432. Epub 2010 Jan 27.

13 ABC News: Fosamax: Is Long Term Use of Bone Strengthening Drug Linked to Fractures? http://abcnews.go.com/GMA/OnCall/fosamax-long-term-bone-strengthening-drug-linked-fractures/story?id=10045179

14 Ueki S, Kasai T, Takato J et al. Production of a fall prevention exercise program considering suggestions from community-dwelling elderly. Nippon Koshu Eisei Zasshi. 2006;53(2):112-121.


Osteoporosis Raises Risk of Bone Fractures - You Need Osteoporosis Protection for Life!

No one wants creaky bones, but the number of hospitalizations for osteoporosis-related fractures has increased in the United States, jumping 55% since 1995. The Agency for Healthcare Research and Quality says more than 254,000 hospital stays are due to injuries stemming from osteoporosis.

That’s why Dr. Fuhrman made a DVD called Osteoporosis Protection for Life. In it he explains what you can do to keep your bones strong and healthy, with exercise, improved diet and supplements.

Most people mistakenly are led to believe that drugs are the answer to treating osteopenia and osteoporosis. However, studies reveal that the bisphosphonates, like Actonel, Fosamax, Boniva, and Reclast, commonly prescribed for osteoporosis, are not as effective as we have been led to believe. As more and more research data comes out about the long-term risks of these medications, we are finding out that they are more dangerous than we had previously thought.

I want to give people the information they need to put an effective plan into action. In this video, I offer my advice regarding diet, supplements, and exercise. I am joined by my wife, Lisa, and staff to demonstrate the best exercises to effectively build your strength and bone mass. We've even added a fun 15 minute workout to start you on your way. Now is the time to take control of your health destiny!

For more, here’s a preview clip of Osteoporosis Protection for Life.

Image credit: DrFuhrman.com